MD, Full professor of Molecular Biology at the Faculty of Medicine and Psychology of the Sapienza University of Rome. Director of the Advanced Molecular Diagnostics Unit of the Sant’Andrea Hospital of Rome; CO-founder and secretary of the Italian Society of Personalised Medicine. h
-index 35. Service: Laboratory for Advanced Molecular Diagnostics (Sant’Andrea Hospital of Rome) is a Personalised Medicine Service for General Medicine, Cardiology, Oncology, Psychiatry, Neurology, Surgery and others (partial list of analysis available at http://w3.uniroma1.it/biocmed2/dima/english_version.htm
). Mainly based on “-omics” approach for pre-emptive medicine, it has been developed by collaboration between National Italian Health Service and Sapienza University of Rome. M. Simmaco has been the Director from foundation (2002) to present. He is co-chair of the Communication and External Relations Division of the European Society of Pharmacogenomics and Personalised Therapy (ESPT) since 2013 (www.esptnet.eu
Relevant peer-reviewed publications
- Mariani S, Lionetto L, Cavallari M, Tubaro A, Rasio D, De Nunzio C, Hong GM, Borro M, Simmaco M. Low prostate concentration of lycopene is associated with development of prostate cancer in patients with high-grade prostatic intraepithelial neoplasia. Int J Mol Sci. 2014 Jan 21; 15(1): 1433-40.
- Francia P, Adduci C, Semprini L, …, Simmaco M, Volpe M. Osteopontin and Galectin-3 Predict the Risk of Ventricular Tachycardia and Fibrillation in Heart Failure Patients with Implantable Defibrillators. J Cardiovasc Electrophysiol. 2014 Jun; 25(6): 609-16.
- Francia P, Balla C, Ricotta A, …, Simmaco M, …, Volpe M. Plasma osteopontin reveals left ventricular reverse remodelling following cardiac resynchronization therapy in heart failure. Int J Cardiol. 2011 Dec 15; 153(3): 306-10.
- Ruggeri M, Bonetto C, Lasalvia A, De Girolamo G, Fioritti A, Rucci P et al. A multi-element psychosocial intervention for early psychosis (GET UP PIANO TRIAL) conducted in a catchment area of 10 million inhabitants: study protocol for a pragmatic cluster randomised controlled trial. Trials. 2012 May 30; 13:73.
Nasca C, Xenos D, Barone Y, Caruso A, Scaccianoce S, Matrisciano F, Battaglia G, Mathé AA, Pittaluga A, Lionetto L, Simmaco M
, Nicoletti F. L-acetylcarnitine causes rapid antidepressant effects through the epigenetic induction of mGlu2 receptors. Proc Natl Acad Sci U S A. 2013 Mar 19; 110(12): 4804-9.